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Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development- [electronic resource]
Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development- [electronic resource]
상세정보
- 자료유형
- 학위논문(국외)
- 자관 청구기호
- 기본표목-개인명
- 표제와 책임표시사항
- Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development - [electronic resource] / Sarah C. Vogel
- 발행, 배포, 간사 사항
- 발행, 배포, 간사 사항
- 형태사항
- 1 online resource(p.137 )
- 일반주기
- Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
- 일반주기
- Advisor: Brito, Natalie.
- 학위논문주기
- Thesis (Ph.D.)--New York University, 2023.
- 이용제한주기
- This item must not be sold to any third party vendors.
- 요약 등 주기
- 요약Decades of research have demonstrated that early life stress can influence the development of multiple biological and psychological systems. Recently, the system of bacteria living in the gastrointestinal tract, known as the gut microbiome, has received increasing attention and interest as a potential mechanism by which stress influences development. The aim of this dissertation is to investigate the role of the gut microbiome as a potential mechanism linking common experiences of early life stress with differences in cognitive and emotional development in infancy. Through three studies across two samples I examined how stress is associated with the composition and diversity of the gut microbiome (paper 1), how the gut microbiome is associated with neural and behavioral markers of recognition memory (paper 2), and how associations between the gut microbiome and infant emotion regulation differ as a function of caregiver stress (paper 3). These three papers together add to a growing body of literature demonstrating the gut microbiome as an important biological system shaping cognitive development and mental health. In paper 1, we examined associations between caregiver physiological stress and family material strain and the diversity and composition of the infant gut microbiota at 12 months of age. We found a significant, positive association between caregiver physiological stress and diversity of the gut microbiota. Paper 2 extended these findings in the same sample and examined associations between the gut microbiome and neural and behavioral measures of recognition memories at 15 months. We identified abundance of several genera associated with recognition memory, including an unknown genus from the Lachnospiraceae family that was negatively associated with both neural and behavioral measures. In paper 3, we examined associations between the gut microbiome and infant emotion regulation, and how these associations differed based on caregiver stress. We identified one species of bacteria, Streptococcus salivarius, whose abundance was negatively associated with infant emotion regulation. Altogether, this dissertation presents a step forward in our scientific understanding of the role of the gut microbiome in typical development during infancy and highlights how variations in common experiences of stress may relate to population-level trends in mental and physical health.
- 주제명부출표목-일반주제명
- 주제명부출표목-일반주제명
- 주제명부출표목-일반주제명
- 주제명부출표목-일반주제명
- 비통제 색인어
- 비통제 색인어
- 비통제 색인어
- 비통제 색인어
- 비통제 색인어
- 부출표목-단체명
- 기본자료저록
- Dissertations Abstracts International. 85-03B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 원문정보보기
- 소장사항
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202402 2024
MARC
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■040 ▼aMiAaPQ▼cMiAaPQ
■08204▼a136
■090 ▼a전자도서(박사논문)
■1001 ▼aVogel, Sarah C.
■24510▼aGut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development▼h[electronic resource]▼cSarah C. Vogel
■260 ▼a[S.l.]▼bNew York University. ▼c2023
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2023
■300 ▼a1 online resource(p.137 )
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-03, Section: B.
■500 ▼aAdvisor: Brito, Natalie.
■5021 ▼aThesis (Ph.D.)--New York University, 2023.
■506 ▼aThis item must not be sold to any third party vendors.
■520 ▼aDecades of research have demonstrated that early life stress can influence the development of multiple biological and psychological systems. Recently, the system of bacteria living in the gastrointestinal tract, known as the gut microbiome, has received increasing attention and interest as a potential mechanism by which stress influences development. The aim of this dissertation is to investigate the role of the gut microbiome as a potential mechanism linking common experiences of early life stress with differences in cognitive and emotional development in infancy. Through three studies across two samples I examined how stress is associated with the composition and diversity of the gut microbiome (paper 1), how the gut microbiome is associated with neural and behavioral markers of recognition memory (paper 2), and how associations between the gut microbiome and infant emotion regulation differ as a function of caregiver stress (paper 3). These three papers together add to a growing body of literature demonstrating the gut microbiome as an important biological system shaping cognitive development and mental health. In paper 1, we examined associations between caregiver physiological stress and family material strain and the diversity and composition of the infant gut microbiota at 12 months of age. We found a significant, positive association between caregiver physiological stress and diversity of the gut microbiota. Paper 2 extended these findings in the same sample and examined associations between the gut microbiome and neural and behavioral measures of recognition memories at 15 months. We identified abundance of several genera associated with recognition memory, including an unknown genus from the Lachnospiraceae family that was negatively associated with both neural and behavioral measures. In paper 3, we examined associations between the gut microbiome and infant emotion regulation, and how these associations differed based on caregiver stress. We identified one species of bacteria, Streptococcus salivarius, whose abundance was negatively associated with infant emotion regulation. Altogether, this dissertation presents a step forward in our scientific understanding of the role of the gut microbiome in typical development during infancy and highlights how variations in common experiences of stress may relate to population-level trends in mental and physical health.
■590 ▼aSchool code: 0146.
■650 4▼aDevelopmental psychology.
■650 4▼aMicrobiology.
■650 4▼aNeurosciences.
■650 4▼aClinical psychology.
■653 ▼aGut feelings
■653 ▼aGut microbiota
■653 ▼aNeurocognitive development
■653 ▼aBehavioral markers
■653 ▼aRecognition memory
■690 ▼a0620
■690 ▼a0410
■690 ▼a0317
■690 ▼a0622
■71020▼aNew York University▼bApplied Psychology.
■7730 ▼tDissertations Abstracts International▼g85-03B.
■773 ▼tDissertation Abstract International
■790 ▼a0146
■791 ▼aPh.D.
■792 ▼a2023
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16933162▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
■980 ▼a202402▼f2024
