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Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship- [electronic resource]
Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship- [electronic resource]
상세정보
- 자료유형
- 학위논문(국외)
- 자관 청구기호
- 기본표목-개인명
- 표제와 책임표시사항
- Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship - [electronic resource] / Maryam Hamidi
- 발행, 배포, 간사 사항
- 발행, 배포, 간사 사항
- 형태사항
- 1 online resource(p.118 )
- 일반주기
- Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
- 일반주기
- Advisor: Darrah, Rebecca; Levine, Alan.
- 학위논문주기
- Thesis (Ph.D.)--Case Western Reserve University, 2021.
- 이용제한주기
- This item must not be sold to any third party vendors.
- 요약 등 주기
- 요약The primary intestinal microbial colonization in preterm infants (PIs) is influenced by gestational age (GA), delivery mode, and antibiotics exposure. There are few effective interventions designed to improve microbial colonization among PIs, and therefore this is a critical issue for nurses in the neonatal intensive care unit (NICU). This work introduces three independent studies that have direct or indirect impact on improving the gut microbial colonization among PIs. Study number one was a descriptive observational study to explore the impact of skin -to-skin care on intestinal microbial diversity and composition of PIs. The participants of the study were 25 mother-infant dyads (infants 'GA: 31-34 weeks). Mothers recorded the duration of skin-to-skin care in a diary and infants were subsequently divided in low and high groups of skin-to-skin care. The microbial DNA from mother's chest skin swab and infants' oral swabs and stool samples were analyzed using 16s rRNA gene sequencing. Our results showed differences in intestinal microbial composition and diversity between low and high groups of skin-to-skin care. That suggests that STS care may affect the microbial composition and diversity in the gut of preterm infants. Antibiotics are a major risk factor which disturbs gut microbial colonization. Antibiotics are the most prescribed medications in the NICUs. Antibiotic stewardship programs have reduced the unnecessary antibiotic therapy. The second study is a review of literature about the concept of antimicrobial stewardship. It also identifies the obstacles which prevent nursing teams from implementing the principles of antimicrobial stewardship in the NICUs. The third study is a descriptive survey study that identifies nurses' attitudes toward antibiotic stewardship programs in the NICUs. The survey questionnaire was posted on the National Association of Neonatal Network (NANN). The results of this study identified that although the majority of nurses were very familiar with the term "antibiotic stewardship", their responses to the questions related to the component of antibiotic stewardship program were inconsistent. In summary these studies are important to help identify solutions to enhance the primary seeding of microbial communities among the vulnerable population of preterm infants.
- 주제명부출표목-일반주제명
- 주제명부출표목-일반주제명
- 주제명부출표목-일반주제명
- 주제명부출표목-일반주제명
- 비통제 색인어
- 비통제 색인어
- 비통제 색인어
- 비통제 색인어
- 비통제 색인어
- 부출표목-단체명
- 기본자료저록
- Dissertations Abstracts International. 85-03B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 원문정보보기
- 소장사항
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202402 2024
MARC
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■090 ▼a전자도서(박사논문)
■1001 ▼aHamidi, Maryam.
■24510▼aMicrobiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship▼h[electronic resource]▼cMaryam Hamidi
■260 ▼a[S.l.]▼bCase Western Reserve University. ▼c2021
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2021
■300 ▼a1 online resource(p.118 )
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-03, Section: B.
■500 ▼aAdvisor: Darrah, Rebecca; Levine, Alan.
■5021 ▼aThesis (Ph.D.)--Case Western Reserve University, 2021.
■506 ▼aThis item must not be sold to any third party vendors.
■520 ▼aThe primary intestinal microbial colonization in preterm infants (PIs) is influenced by gestational age (GA), delivery mode, and antibiotics exposure. There are few effective interventions designed to improve microbial colonization among PIs, and therefore this is a critical issue for nurses in the neonatal intensive care unit (NICU). This work introduces three independent studies that have direct or indirect impact on improving the gut microbial colonization among PIs. Study number one was a descriptive observational study to explore the impact of skin -to-skin care on intestinal microbial diversity and composition of PIs. The participants of the study were 25 mother-infant dyads (infants 'GA: 31-34 weeks). Mothers recorded the duration of skin-to-skin care in a diary and infants were subsequently divided in low and high groups of skin-to-skin care. The microbial DNA from mother's chest skin swab and infants' oral swabs and stool samples were analyzed using 16s rRNA gene sequencing. Our results showed differences in intestinal microbial composition and diversity between low and high groups of skin-to-skin care. That suggests that STS care may affect the microbial composition and diversity in the gut of preterm infants. Antibiotics are a major risk factor which disturbs gut microbial colonization. Antibiotics are the most prescribed medications in the NICUs. Antibiotic stewardship programs have reduced the unnecessary antibiotic therapy. The second study is a review of literature about the concept of antimicrobial stewardship. It also identifies the obstacles which prevent nursing teams from implementing the principles of antimicrobial stewardship in the NICUs. The third study is a descriptive survey study that identifies nurses' attitudes toward antibiotic stewardship programs in the NICUs. The survey questionnaire was posted on the National Association of Neonatal Network (NANN). The results of this study identified that although the majority of nurses were very familiar with the term "antibiotic stewardship", their responses to the questions related to the component of antibiotic stewardship program were inconsistent. In summary these studies are important to help identify solutions to enhance the primary seeding of microbial communities among the vulnerable population of preterm infants.
■590 ▼aSchool code: 0042.
■650 4▼aNursing.
■650 4▼aMicrobiology.
■650 4▼aObstetrics.
■650 4▼aImmunology.
■653 ▼aPreterm infant
■653 ▼aAntibiotic stewardship
■653 ▼aMicrobiome
■653 ▼aMother-infant dyads
■653 ▼aSkin-to-skin care
■690 ▼a0569
■690 ▼a0982
■690 ▼a0410
■690 ▼a0380
■71020▼aCase Western Reserve University▼bNursing.
■7730 ▼tDissertations Abstracts International▼g85-03B.
■773 ▼tDissertation Abstract International
■790 ▼a0042
■791 ▼aPh.D.
■792 ▼a2021
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16935485▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
■980 ▼a202402▼f2024
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